JOIAL 32mg 2ml

Description

JOIAL 2ml 1.6% (32 mg) prefilled syringes
Hyaluronic acid sodium salt
Joial, provides a linear intermediate (~1,000-1,500 KDa) Molecular Weight Hyaluronic Acid (HA) for intra-articular viscosupplementation.

MECHANICAL ACTIVITY

• restoring viscoelastic properties of synovial fluid
• shock absorption
• lubrication
• reducing stifness

CHONDROPROTECTION ACTIVITY

• preventing cartilage degeneration by oxidative stress inhibition
• stimulating the endogenous synthesis of HA by synovial fibroblasts

ANALGESIC ACTIVITY

• reducing the induction of pain mediators
• interacting with HA receptors on or around the free nerve endings

ANTI-INFLAMMATORY ACTIVITY

• suppressing proinflammatory mediators: IL8, IL6,PGE2 TNFα
  • inhibiting migration and aggregation of leukocyte and macrophages